CMap Candidate Details

Structure:
CMap ID: C13674
Pert ID: BRD-K35573744
Compound Name: erbstatin-analog
Targets: EGFR
MoA: EGFR inhibitor; Tyrosine kinase inhibitor
SMILES: COC(=O)C=Cc1cc(O)ccc1O
InchiKey: BQCNSTFWSKOWMA-GORDUTHDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49833 BRD-K35573744 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50178 BRD-K35573744 HA1E 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.66
50354 BRD-K35573744 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50526 BRD-K35573744 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50664 BRD-K35573744 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50925 BRD-K35573744 PC3 10 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.37
51027 BRD-K35573744 VCAP 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
96134 BRD-K35573744 A549 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).