CMap Candidate Details

Structure:
CMap ID: C13693
Pert ID: BRD-K35629949
Compound Name: SR-27897
Targets: CCKAR
MoA: CCK receptor antagonist
SMILES: OC(=O)Cn1c(cc2ccccc12)C(=O)Nc1nc(cs1)-c1ccccc1Cl
InchiKey: ILNRQFBVVQUOLP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4423 BRD-K35629949 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4925 BRD-K35629949 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39680 BRD-K35629949 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39993 BRD-K35629949 HEPG2 10 uM 6 h 0.28 1.16 0.35 0.0 0.0 0.0
40799 BRD-K35629949 NEU 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
41102 BRD-K35629949 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41435 BRD-K35629949 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90628 BRD-K35629949 HCT116 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90662 BRD-K35629949 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97242 BRD-K35629949 PC3 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
97987 BRD-K35629949 HA1E 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
98063 BRD-K35629949 P1A82 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
99877 BRD-K35629949 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120573 BRD-K35629949 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120678 BRD-K35629949 HT29 0.37 uM 24 h 0.34 1.41 1.03 0.0 0.0 0.0
120731 BRD-K35629949 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.31
120839 BRD-K35629949 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
128993 BRD-K35629949 A375 0.74 uM 24 h 0.26 1.1 0.24 -0.25 -0.84 0.17
129024 BRD-K35629949 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129066 BRD-K35629949 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).