CMap Candidate Details

Structure:
CMap ID: C13707
Pert ID: BRD-K35687265
Compound Name: ON-01910
Targets: PLK2; FLT1; FYN; PDGFRA; PLK1; SRC; CDK1
MoA: PLK inhibitor
SMILES: COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(NCC=O)c2)c(OC)c1
InchiKey: POSHWWRILMRTTE-JXMROGBWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29835 BRD-K35687265 A375 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
30425 BRD-K35687265 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30733 BRD-K35687265 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31024 BRD-K35687265 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31329 BRD-K35687265 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.34 1.85
31525 BRD-K35687265 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31864 BRD-K35687265 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32409 BRD-K35687265 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32630 BRD-K35687265 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
33008 BRD-K35687265 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33277 BRD-K35687265 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96135 BRD-K35687265 A549 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).