CMap Candidate Details

Structure:
CMap ID: C01376
Pert ID: BRD-A57382968
Compound Name: piroxicam
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CN1C(C(=O)Nc2ccccn2)C(=O)c2ccccc2S1(=O)=O
InchiKey: MNSCVRXKDINXEY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5531 BRD-A57382968 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6474 BRD-A57382968 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
24538 BRD-A57382968 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24991 BRD-A57382968 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37523 BRD-A57382968 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37834 BRD-A57382968 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38372 BRD-A57382968 NPC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
90922 BRD-A57382968 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
97572 BRD-A57382968 NKDBA 3.33 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
123563 BRD-A57382968 HEK293 0.04 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
123614 BRD-A57382968 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123641 BRD-A57382968 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123680 BRD-A57382968 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131973 BRD-A57382968 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132006 BRD-A57382968 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
132104 BRD-A57382968 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132134 BRD-A57382968 YAPC 0.01 uM 24 h 0.19 0.78 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).