CMap Candidate Details

Structure:
CMap ID: C01377
Pert ID: BRD-A57457122
Compound Name: VU-0400071-3
Targets: GRM4
MoA: Glutamate receptor modulator
SMILES: Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)CC(C1=O)c1ccccc1
InchiKey: UYGDCIXFYIWDMR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
18902 BRD-A57457122 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19388 BRD-A57457122 A549 10 uM 6 h 0.23 0.96 0.07 0.2 0.69 0.01
19553 BRD-A57457122 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.73
19873 BRD-A57457122 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20203 BRD-A57457122 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20535 BRD-A57457122 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21005 BRD-A57457122 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21173 BRD-A57457122 PC3 10 uM 24 h -0.2 -0.82 0.0 0.38 1.33 1.72
21496 BRD-A57457122 VCAP 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).