CMap Candidate Details

Structure:
CMap ID: C13815
Pert ID: BRD-K36009368
Compound Name: NNC-63-0532
Targets: OPRL1
MoA: Opioid receptor agonist
SMILES: COC(=O)CN1CN(c2ccccc2)C3(CCN(Cc4ccc5ccccc5c4)CC3)C1=O
InchiKey: DSEIKQVUTKGLGT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4102 BRD-K36009368 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4567 BRD-K36009368 HCC515 10 uM 6 h -0.23 -0.97 0.11 0.28 0.99 0.4
4682 BRD-K36009368 PC3 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
4926 BRD-K36009368 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
39127 BRD-K36009368 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39320 BRD-K36009368 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39683 BRD-K36009368 ASC 10 uM 24 h -0.23 -0.98 0.11 0.23 0.82 0.1
39996 BRD-K36009368 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.39 2.02
40268 BRD-K36009368 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40466 BRD-K36009368 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41105 BRD-K36009368 NPC 10 uM 24 h -0.25 -1.04 0.2 0.0 0.0 0.0
41438 BRD-K36009368 SKB 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
99883 BRD-K36009368 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).