CMap Candidate Details

Structure:
CMap ID: C13827
Pert ID: BRD-K36038115
Compound Name: BRD-K36038115
Targets: NPBWR1
MoA: Neuropeptide receptor antagonist
SMILES: COc1ccc(Oc2c(Cl)cnn(-c3cc(C)cc(C)c3)c2=O)cc1
InchiKey: RTIGBOQZDVBXCO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19022 BRD-K36038115 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19451 BRD-K36038115 A549 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
19669 BRD-K36038115 HA1E 10 uM 6 h 0.0 0.0 0.0 0.28 0.97 0.36
19995 BRD-K36038115 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20326 BRD-K36038115 HEPG2 10 uM 6 h 0.22 0.9 0.03 0.31 1.09 0.67
20896 BRD-K36038115 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21420 BRD-K36038115 PC3 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
21739 BRD-K36038115 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.47
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).