CMap Candidate Details

Structure:
CMap ID: C13833
Pert ID: BRD-K36055864
Compound Name: cycloheximide
Targets: RPL3
MoA: Protein synthesis inhibitor
SMILES: C[C@H]1C[C@H](C)C(=O)[C@@H](C1)[C@H](O)CC1CC(=O)NC(=O)C1
InchiKey: YPHMISFOHDHNIV-FSZOTQKASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5321 BRD-K36055864 HA1E 10 uM 24 h 0.28 1.16 0.35 -0.29 -0.96 0.43
5615 BRD-K36055864 HCC515 10 uM 24 h 0.25 1.04 0.14 -0.38 -1.29 1.5
5905 BRD-K36055864 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.44 -1.48 15.35
6091 BRD-K36055864 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.57
6274 BRD-K36055864 PC3 10 uM 6 h 0.31 1.3 0.69 -0.55 -1.84 15.65
44376 BRD-K36055864 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44575 BRD-K36055864 A549 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
44938 BRD-K36055864 ASC 10 uM 24 h 0.32 1.33 0.85 0.0 0.0 0.0
45506 BRD-K36055864 HT29 10 uM 6 h 0.0 0.0 0.0 -0.48 -1.62 15.65
46693 BRD-K36055864 SKB 10 uM 24 h 0.21 0.86 0.01 -0.31 -1.05 0.7
53580 BRD-K36055864 HUH7 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53656 BRD-K36055864 PHH 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
88551 BRD-K36055864 VCAP 10 uM 6 h 0.21 0.89 0.02 -0.38 -1.27 1.39
98143 BRD-K36055864 NPC 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.52 15.35
98375 BRD-K36055864 NEU 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
99885 BRD-K36055864 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).