CMap Candidate Details

Structure:
CMap ID: C01391
Pert ID: BRD-A58207013
Compound Name: pinacidil
Targets: ABCC9; ABCC8
MoA: ATP channel activator; Potassium channel activator
SMILES: CC(NC(=NC#N)Nc1ccncc1)C(C)(C)C
InchiKey: IVVNZDGDKPTYHK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1503 BRD-A58207013 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2043 BRD-A58207013 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.9
2344 BRD-A58207013 PC3 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
2752 BRD-A58207013 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39051 BRD-A58207013 A375 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
39400 BRD-A58207013 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39574 BRD-A58207013 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39900 BRD-A58207013 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40184 BRD-A58207013 HT29 10 uM 6 h 0.0 0.0 0.0 -0.18 -0.62 0.0
40570 BRD-A58207013 MCF??7.00 10 uM 6 h -0.25 -1.06 0.25 0.0 0.0 0.0
41000 BRD-A58207013 NPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
41323 BRD-A58207013 SKB 10 uM 24 h -0.19 -0.8 0.0 -0.33 -1.09 0.84
100240 BRD-A58207013 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).