CMap Candidate Details

Structure:
CMap ID: C13911
Pert ID: BRD-K36234266
Compound Name: carmustine
Targets: GSR
MoA: DNA inhibitor; DNA alkylating agent
SMILES: [O-][N+]N(CCCl)C(=O)NCCCl
InchiKey: DLGOEMSEDOSKAD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
116293 BRD-K36234266 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
116335 BRD-K36234266 A549 1.11 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
116377 BRD-K36234266 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116424 BRD-K36234266 HCC515 10 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
116476 BRD-K36234266 HEPG2 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
116526 BRD-K36234266 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
116573 BRD-K36234266 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116612 BRD-K36234266 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).