CMap Candidate Details

Structure:
CMap ID: C13917
Pert ID: BRD-K36258877
Compound Name: AZ-10417808
Targets: CASP3
MoA: Caspase inhibitor
SMILES: [O-][N+](=O)c1cc(C(=O)NCC=C)c2nc(Nc3ccc(Cl)c(Cl)c3)[nH]c(=O)c2c1
InchiKey: VUBILPOZTRGZJK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3011 BRD-K36258877 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3359 BRD-K36258877 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3615 BRD-K36258877 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3778 BRD-K36258877 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44377 BRD-K36258877 A375 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
44576 BRD-K36258877 A549 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
44939 BRD-K36258877 ASC 10 uM 24 h 0.26 1.07 0.19 -0.31 -1.05 0.71
45237 BRD-K36258877 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45507 BRD-K36258877 HT29 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.15
45812 BRD-K36258877 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46058 BRD-K36258877 NPC 10 uM 24 h 0.27 1.11 0.25 0.3 1.07 0.62
46374 BRD-K36258877 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46694 BRD-K36258877 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99887 BRD-K36258877 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).