CMap Candidate Details

Structure:
CMap ID: C13923
Pert ID: BRD-K36270037
Compound Name: esculin
Targets: --
MoA: --
SMILES: OC[C@H]1O[C@@H](Oc2cc3ccc(=O)oc3cc2O)[C@@H](O)[C@@H](O)[C@@H]1O
InchiKey: XHCADAYNFIFUHF-JSFFLRCESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121791 BRD-K36270037 HT29 3.33 uM 24 h 0.26 1.06 0.19 0.0 0.0 0.0
129753 BRD-K36270037 A375 0.03 uM 24 h -0.21 -0.86 0.01 0.0 0.0 0.0
129787 BRD-K36270037 HA1E 0.03 uM 24 h -0.28 -1.15 0.44 -0.32 -1.07 0.78
129821 BRD-K36270037 HEK293 2.22 uM 24 h 0.27 1.11 0.26 -0.3 -1.02 0.61
129870 BRD-K36270037 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129948 BRD-K36270037 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.18 0.64 0.0
129995 BRD-K36270037 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130032 BRD-K36270037 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
130079 BRD-K36270037 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.74
130104 BRD-K36270037 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130152 BRD-K36270037 YAPC 0.03 uM 24 h 0.3 1.25 0.53 0.35 1.23 1.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).