CMap Candidate Details

Structure:
CMap ID: C13952
Pert ID: BRD-K36363294
Compound Name: I-BET-151
Targets: --
MoA: --
SMILES: COc1cc2c3n([C@H](C)c4ccccn4)c(=O)[nH]c3cnc2cc1-c1c(C)noc1C
InchiKey: VUVUVNZRUGEAHB-CYBMUJFWSA-N
Compound Aliases: GSK-1210151A

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90308 BRD-K36363294 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
93620 BRD-K36363294 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93685 BRD-K36363294 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
93722 BRD-K36363294 CD34 0.37 uM 24 h -0.25 -1.06 0.25 -0.37 -1.25 1.35
93763 BRD-K36363294 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93798 BRD-K36363294 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93848 BRD-K36363294 HEK293 10 uM 24 h 0.23 0.96 0.07 -0.42 -1.41 2.02
93892 BRD-K36363294 HELA 3.33 uM 24 h 0.31 1.31 0.76 -0.34 -1.13 0.98
93932 BRD-K36363294 HEPG2 0.37 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
93992 BRD-K36363294 HUVEC 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.27
94032 BRD-K36363294 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94065 BRD-K36363294 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
94111 BRD-K36363294 NEU 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
94158 BRD-K36363294 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.39
94245 BRD-K36363294 SHSY5Y 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94297 BRD-K36363294 SKL 3.33 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.3
94342 BRD-K36363294 THP1 0.12 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
94384 BRD-K36363294 YAPC 10 uM 24 h 0.31 1.3 0.72 -0.18 -0.61 0.0
97102 BRD-K36363294 PC3 10 uM 24 h 0.24 0.99 0.1 -0.43 -1.44 15.35
97289 BRD-K36363294 HAP1 3.33 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
97362 BRD-K36363294 A375 3.33 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
118883 BRD-K36363294 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).