CMap Candidate Details

Structure:
CMap ID: C13963
Pert ID: BRD-K36395411
Compound Name: SB-206553
Targets: HTR2B; HTR2C
MoA: Serotonin receptor antagonist
SMILES: Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1
InchiKey: QJQORSLQNXDVGE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6875 BRD-K36395411 A375 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
6990 BRD-K36395411 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7311 BRD-K36395411 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7647 BRD-K36395411 HCC515 10 uM 6 h -0.25 -1.05 0.24 -0.25 -0.83 0.17
7858 BRD-K36395411 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
8281 BRD-K36395411 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8362 BRD-K36395411 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
8812 BRD-K36395411 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).