CMap Candidate Details

Structure:
CMap ID: C13982
Pert ID: BRD-K36467523
Compound Name: bindarit
Targets: CCL2; CCL7; CCL8
MoA: NFKB pathway inhibitor
SMILES: CC(C)(OCc1nn(Cc2ccccc2)c2ccccc12)C(O)=O
InchiKey: MTHORRSSURHQPZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120579 BRD-K36467523 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120684 BRD-K36467523 HT29 3.33 uM 24 h 0.21 0.86 0.01 -0.38 -1.29 1.52
120738 BRD-K36467523 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120846 BRD-K36467523 YAPC 0.04 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
128997 BRD-K36467523 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129015 BRD-K36467523 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129025 BRD-K36467523 HELA 0.08 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
129071 BRD-K36467523 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129088 BRD-K36467523 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).