CMap Candidate Details

Structure:
CMap ID: C13997
Pert ID: BRD-K36529613
Compound Name: PU-H71
Targets: HSP90AA1
MoA: HSP inhibitor
SMILES: CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12
InchiKey: SUPVGFZUWFMATN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33675 BRD-K36529613 A375 10 uM 6 h 0.21 0.89 0.02 -0.25 -0.85 0.19
33802 BRD-K36529613 A549 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
34091 BRD-K36529613 ASC 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
34355 BRD-K36529613 HA1E 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.06
34608 BRD-K36529613 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
34875 BRD-K36529613 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35138 BRD-K36529613 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35450 BRD-K36529613 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35561 BRD-K36529613 NEU 10 uM 24 h 0.0 0.0 0.0 0.41 1.46 2.23
35774 BRD-K36529613 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35954 BRD-K36529613 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36253 BRD-K36529613 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36548 BRD-K36529613 SKB 10 uM 24 h 0.0 0.0 0.0 0.38 1.35 1.72
36814 BRD-K36529613 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).