CMap Candidate Details

Structure:
CMap ID: C00014
Pert ID: BRD-A00520476
Compound Name: otenzepad
Targets: CHRM1; CHRM2
MoA: Acetylcholine receptor antagonist
SMILES: CCN(CC)CC1CCCCN1CC(=O)N1c2ccccc2C(=O)Nc2cccnc12
InchiKey: UBRKDAVQCKZSPO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24368 BRD-A00520476 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24638 BRD-A00520476 A549 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.13
24709 BRD-A00520476 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24830 BRD-A00520476 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.68
24978 BRD-A00520476 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25121 BRD-A00520476 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25274 BRD-A00520476 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).