CMap Candidate Details

Structure:
CMap ID: C14027
Pert ID: BRD-K36627727
Compound Name: tamibarotene
Targets: RARA; RARB
MoA: Retinoid receptor agonist
SMILES: CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(O)=O)ccc12
InchiKey: MUTNCGKQJGXKEM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1345 BRD-K36627727 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
34092 BRD-K36627727 ASC 10 uM 24 h -0.28 -1.17 0.49 0.0 0.0 0.0
34876 BRD-K36627727 HEPG2 10 uM 6 h -0.3 -1.25 0.7 -0.47 -1.58 15.65
35562 BRD-K36627727 NEU 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.46
35775 BRD-K36627727 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36254 BRD-K36627727 PHH 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
36549 BRD-K36627727 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
36815 BRD-K36627727 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120537 BRD-K36627727 A375 3.33 uM 24 h -0.22 -0.91 0.05 0.24 0.86 0.16
120583 BRD-K36627727 A549 3.33 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
120611 BRD-K36627727 HA1E 3.33 uM 24 h 0.19 0.77 0.0 0.0 0.0 0.0
120688 BRD-K36627727 HT29 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
120742 BRD-K36627727 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120795 BRD-K36627727 PC3 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
120850 BRD-K36627727 YAPC 1.11 uM 24 h -0.28 -1.16 0.45 0.28 0.99 0.41
129026 BRD-K36627727 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129074 BRD-K36627727 MCF??7.00 0.08 uM 24 h -0.25 -1.02 0.19 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).