CMap Candidate Details

Structure:
CMap ID: C01405
Pert ID: BRD-A58955223
Compound Name: sulforaphane
Targets: NFE2L2
MoA: Anti-cancer agent; Aryl hydrocarbon receptor antagonist
SMILES: CS(=O)CCCCN=C=S
InchiKey: SUVMJBTUFCVSAD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9148 BRD-A58955223 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9297 BRD-A58955223 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9601 BRD-A58955223 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10010 BRD-A58955223 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10408 BRD-A58955223 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10676 BRD-A58955223 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.53
10909 BRD-A58955223 HT29 10 uM 24 h 0.2 0.83 0.0 -0.26 -0.87 0.23
11250 BRD-A58955223 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
11349 BRD-A58955223 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11662 BRD-A58955223 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11921 BRD-A58955223 NCIH596 10 uM 6 h -0.28 -1.17 0.49 0.0 0.0 0.0
12212 BRD-A58955223 NOMO1 10 uM 6 h -0.27 -1.14 0.42 0.23 0.82 0.1
12999 BRD-A58955223 THP1 10 uM 6 h -0.23 -0.96 0.09 0.32 1.14 0.85
13157 BRD-A58955223 U937 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
13540 BRD-A58955223 VCAP 10 uM 6 h 0.18 0.76 0.0 0.29 1.03 0.52
53281 BRD-A58955223 MCF10A 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119089 BRD-A58955223 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119362 BRD-A58955223 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
119890 BRD-A58955223 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.03 0.62
123521 BRD-A58955223 A375 3.33 uM 24 h 0.29 1.21 0.46 0.0 0.0 0.0
123584 BRD-A58955223 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
123623 BRD-A58955223 HELA 10 uM 24 h 0.25 1.05 0.16 -0.24 -0.82 0.15
123770 BRD-A58955223 YAPC 10 uM 24 h 0.3 1.26 0.57 0.34 1.19 1.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).