CMap Candidate Details

Structure:
CMap ID: C14065
Pert ID: BRD-K36732695
Compound Name: setiptiline
Targets: HRH1; HTR2A; HTR2C
MoA: Adrenergic receptor antagonist
SMILES: CN1CCC2=C(C1)c1ccccc1Cc1ccccc21
InchiKey: GVPIXRLYKVFFMK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120538 BRD-K36732695 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120584 BRD-K36732695 A549 0.04 uM 24 h -0.25 -1.06 0.25 0.0 0.0 0.0
120689 BRD-K36732695 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
120743 BRD-K36732695 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120763 BRD-K36732695 MCF??7.00 0.125 uM 24 h 0.16 0.67 0.0 0.0 0.0 0.0
120851 BRD-K36732695 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129017 BRD-K36732695 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129045 BRD-K36732695 HELA 0.08 uM 3 h 0.23 0.96 0.07 0.25 0.87 0.17
129089 BRD-K36732695 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).