CMap Candidate Details

Structure:
CMap ID: C14116
Pert ID: BRD-K36864847
Compound Name: BD-1047
Targets: SIGMAR1
MoA: Adrenergic receptor antagonist
SMILES: CN(C)CCN(C)CCc1ccc(Cl)c(Cl)c1
InchiKey: MGVRNMUKTZOQOW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2874 BRD-K36864847 HA1E 10 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
3360 BRD-K36864847 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3617 BRD-K36864847 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3779 BRD-K36864847 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44380 BRD-K36864847 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44578 BRD-K36864847 A549 10 uM 24 h 0.0 0.0 0.0 0.37 1.31 1.59
44942 BRD-K36864847 ASC 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
45240 BRD-K36864847 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45510 BRD-K36864847 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45689 BRD-K36864847 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46061 BRD-K36864847 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46377 BRD-K36864847 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46697 BRD-K36864847 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).