CMap Candidate Details

Structure:
CMap ID: C01415
Pert ID: BRD-A59303141
Compound Name: quinethazone
Targets: SLC12A3
MoA: Thiazide diuretic
SMILES: CCC1NC(=O)c2cc(c(Cl)cc2N1)S(N)(=O)=O
InchiKey: AGMMTXLNIQSRCG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6663 BRD-A59303141 A375 10 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
7093 BRD-A59303141 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7564 BRD-A59303141 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7959 BRD-A59303141 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.43
8315 BRD-A59303141 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8598 BRD-A59303141 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52100 BRD-A59303141 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100243 BRD-A59303141 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).