CMap Candidate Details

Structure:
CMap ID: C14223
Pert ID: BRD-K37206356
Compound Name: rhamnetin
Targets: ALOX5
MoA: Aldose reductase inhibitor
SMILES: COc1cc(O)c2c(=O)c(O)c(oc2c1)c3ccc(O)c(O)c3
InchiKey: JGUZGNYPMHHYRK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5322 BRD-K37206356 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5617 BRD-K37206356 HCC515 10 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.01
5906 BRD-K37206356 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6184 BRD-K37206356 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6540 BRD-K37206356 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37148 BRD-K37206356 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37284 BRD-K37206356 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37644 BRD-K37206356 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38076 BRD-K37206356 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38199 BRD-K37206356 MCF??7.00 10 uM 24 h -0.24 -1.0 0.14 -0.36 -1.21 1.24
38470 BRD-K37206356 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38946 BRD-K37206356 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).