CMap Candidate Details

Structure:
CMap ID: C01427
Pert ID: BRD-A59943784
Compound Name: fluticasone
Targets: NR3C1; PGR
MoA: Glucocorticoid receptor agonist
SMILES: CC1CC2C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(CC(=O)CO)C(=O)SCF
InchiKey: RZXNVYCLMORIIB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1505 BRD-A59943784 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2044 BRD-A59943784 HCC515 10 uM 6 h -0.25 -1.02 0.18 0.0 0.0 0.0
2159 BRD-A59943784 PC3 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.29 1.53
2643 BRD-A59943784 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41680 BRD-A59943784 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.42
42023 BRD-A59943784 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42222 BRD-A59943784 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42564 BRD-A59943784 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42871 BRD-A59943784 HT29 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
43266 BRD-A59943784 MCF??7.00 10 uM 6 h 0.26 1.08 0.21 0.0 0.0 0.0
43423 BRD-A59943784 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43731 BRD-A59943784 PHH 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).