CMap Candidate Details

Structure:
CMap ID: C14300
Pert ID: BRD-K37392901
Compound Name: NSC-632839
Targets: SENP2; USP1; USP7; USP2
MoA: Ubiquitin specific protease inhibitor
SMILES: Cc1ccc(C=C2CNCC(=Cc3ccc(C)cc3)C2=O)cc1
InchiKey: PKCYYPHSCUSQDK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3014 BRD-K37392901 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3362 BRD-K37392901 HCC515 10 uM 6 h 0.18 0.76 0.0 -0.27 -0.89 0.27
3495 BRD-K37392901 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3959 BRD-K37392901 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44382 BRD-K37392901 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44699 BRD-K37392901 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44945 BRD-K37392901 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45513 BRD-K37392901 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45814 BRD-K37392901 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46063 BRD-K37392901 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46699 BRD-K37392901 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53445 BRD-K37392901 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53581 BRD-K37392901 HUH7 2.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53728 BRD-K37392901 PHH 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.13 0.97
99899 BRD-K37392901 U2OS 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).