CMap Candidate Details

Structure:
CMap ID: C14320
Pert ID: BRD-K37456065
Compound Name: VU-0365114-2
Targets: CHRM5
MoA: M5 modulator
SMILES: FC(F)(F)Oc1ccc2N(Cc3ccc(cc3)-c3ccccc3)C(=O)C(=O)c2c1
InchiKey: SPBGRXOPAXZSER-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16247 BRD-K37456065 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
16659 BRD-K37456065 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16990 BRD-K37456065 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.51 -1.73 15.65
17323 BRD-K37456065 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
17663 BRD-K37456065 HT29 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
17964 BRD-K37456065 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18273 BRD-K37456065 PC3 10 uM 24 h -0.23 -0.94 0.08 -0.32 -1.09 0.84
18587 BRD-K37456065 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).