CMap Candidate Details

Structure:
CMap ID: C14342
Pert ID: BRD-K37516142
Compound Name: idebenone
Targets: --
MoA: --
SMILES: COC1=C(OC)C(=O)C(CCCCCCCCCCO)=C(C)C1=O
InchiKey: JGPMMRGNQUBGND-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24574 BRD-K37516142 A549 10 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
25361 BRD-K37516142 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90959 BRD-K37516142 HUH7 10 uM 72 h 0.24 1.0 0.1 0.26 0.91 0.23
121718 BRD-K37516142 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121733 BRD-K37516142 HA1E 10 uM 24 h -0.29 -1.19 0.54 0.0 0.0 0.0
121788 BRD-K37516142 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.06
121838 BRD-K37516142 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121866 BRD-K37516142 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129817 BRD-K37516142 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
129867 BRD-K37516142 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129944 BRD-K37516142 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
129992 BRD-K37516142 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
130028 BRD-K37516142 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
130100 BRD-K37516142 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).