CMap Candidate Details

Structure:
CMap ID: C14370
Pert ID: BRD-K37590257
Compound Name: GSK-256066
Targets: --
MoA: --
SMILES: COc1cccc(Nc2c(cnc3c(C)cc(cc23)S(=O)(=O)c2cccc(c2)C(=O)N(C)C)C(N)=O)c1
InchiKey: JFHROPTYMMSOLG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96874 BRD-K37590257 A375 3.33 uM 24 h -0.23 -0.94 0.08 -0.37 -1.24 1.31
96949 BRD-K37590257 PC3 10 uM 24 h -0.22 -0.9 0.04 0.24 0.84 0.13
123270 BRD-K37590257 HA1E 10 uM 24 h -0.38 -1.6 15.35 0.0 0.0 0.0
123303 BRD-K37590257 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
123332 BRD-K37590257 HT29 0.37 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
123359 BRD-K37590257 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131538 BRD-K37590257 A549 0.01 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
131611 BRD-K37590257 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131704 BRD-K37590257 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
131757 BRD-K37590257 JURKAT 0.74 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
131841 BRD-K37590257 MCF??7.00 0.03 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
131879 BRD-K37590257 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
131924 BRD-K37590257 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131945 BRD-K37590257 YAPC 0.03 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).