CMap Candidate Details
Structure:
CMap ID: | C00144 |
Pert ID: | BRD-A05680309 |
Compound Name: | BRD-A05680309 |
Targets: | XIAP; CASP8 |
MoA: | XIAP inhibitor; Caspase activator |
SMILES: | CNC(C)C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)NC2CCCc3ccccc23 |
InchiKey: | POKZVJVCUGVHME-UHFFFAOYSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
13718 | BRD-A05680309 | A375 | 10 uM | 24 h | -0.2 | -0.81 | 0.0 | -0.37 | -1.23 | 1.28 |
14186 | BRD-A05680309 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
14561 | BRD-A05680309 | HA1E | 10 uM | 6 h | 0.24 | 1.0 | 0.11 | -0.29 | -0.97 | 0.46 |
14699 | BRD-A05680309 | HCC515 | 10 uM | 6 h | 0.22 | 0.93 | 0.05 | -0.32 | -1.08 | 0.81 |
15179 | BRD-A05680309 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.1 | 0.86 |
15254 | BRD-A05680309 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.05 | 0.57 |
15696 | BRD-A05680309 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
15995 | BRD-A05680309 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |