CMap Candidate Details

Structure:
CMap ID: C01445
Pert ID: BRD-A60571864
Compound Name: budesonide
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=CC5(C)C4[C@@H](O)CC3(C)[C@@]2(O1)C(=O)CO
InchiKey: VOVIALXJUBGFJZ-NECQTEFJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5270 BRD-A60571864 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
5534 BRD-A60571864 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.33 1.71
5850 BRD-A60571864 HEPG2 10 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
5986 BRD-A60571864 HT29 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
6140 BRD-A60571864 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6475 BRD-A60571864 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39052 BRD-A60571864 A375 10 uM 6 h 0.25 1.06 0.18 0.24 0.83 0.12
39401 BRD-A60571864 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39575 BRD-A60571864 ASC 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
40430 BRD-A60571864 MCF??7.00 10 uM 24 h -0.26 -1.08 0.28 0.0 0.0 0.0
40702 BRD-A60571864 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41001 BRD-A60571864 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
41324 BRD-A60571864 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).