CMap Candidate Details

Structure:
CMap ID: C14464
Pert ID: BRD-K37852224
Compound Name: BRD-K37852224
Targets: --
MoA: --
SMILES: C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)CC2CC2)Oc3c(NC(=O)Nc4ccc(cc4)C(F)(F)F)cccc3C1=O
InchiKey: DGVXOYJWIGFWKL-GGUMNFRJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25636 BRD-K37852224 A375 10 uM 6 h -0.19 -0.78 0.0 0.25 0.88 0.18
25935 BRD-K37852224 A549 10 uM 24 h -0.2 -0.85 0.01 0.2 0.72 0.02
26347 BRD-K37852224 ASC 10 uM 24 h -0.23 -0.97 0.11 0.34 1.22 1.15
26682 BRD-K37852224 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
26988 BRD-K37852224 HCC515 10 uM 6 h 0.2 0.85 0.0 0.0 0.0 0.0
27297 BRD-K37852224 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27547 BRD-K37852224 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.64
28236 BRD-K37852224 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28639 BRD-K37852224 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28869 BRD-K37852224 PHH 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
29199 BRD-K37852224 SKB 10 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
29634 BRD-K37852224 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).