CMap Candidate Details

Structure:
CMap ID: C14466
Pert ID: BRD-K37865504
Compound Name: LY-2183240
Targets: FAAH
MoA: FAAH inhibitor; FAAH reuptake inhibitor
SMILES: CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1
InchiKey: GZNIYOXWFCDBBJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4804 BRD-K37865504 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9417 BRD-K37865504 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9725 BRD-K37865504 H1299 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.29
10511 BRD-K37865504 HCT116 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.06
11480 BRD-K37865504 NCIH2073 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
11758 BRD-K37865504 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12044 BRD-K37865504 NCIH596 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
12309 BRD-K37865504 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12786 BRD-K37865504 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12977 BRD-K37865504 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13267 BRD-K37865504 U937 10 uM 6 h -0.26 -1.08 0.31 0.0 0.0 0.0
13471 BRD-K37865504 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39691 BRD-K37865504 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40809 BRD-K37865504 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41112 BRD-K37865504 NPC 10 uM 24 h 0.21 0.87 0.01 -0.32 -1.08 0.81
41447 BRD-K37865504 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53446 BRD-K37865504 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53582 BRD-K37865504 HUH7 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53658 BRD-K37865504 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96851 BRD-K37865504 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99906 BRD-K37865504 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
117707 BRD-K37865504 A549 10 uM 24 h -0.27 -1.11 0.36 0.0 0.0 0.0
117753 BRD-K37865504 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117804 BRD-K37865504 HCC515 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
117903 BRD-K37865504 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117951 BRD-K37865504 MCF??7.00 3.33 uM 24 h -0.21 -0.87 0.02 -0.25 -0.83 0.16
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).