CMap Candidate Details

Structure:
CMap ID: C14495
Pert ID: BRD-K37940862
Compound Name: BRD-K37940862
Targets: NPSR1
MoA: Neuropeptide receptor antagonist
SMILES: Cc1c(n2ccccc2[n+]1CC=Cc1ccccc1)P(=S)(c1ccccc1)c1ccccc1
InchiKey: VSWYSDPXUHVQCG-DTQAZKPQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13927 BRD-K37940862 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
14116 BRD-K37940862 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14454 BRD-K37940862 HA1E 10 uM 24 h -0.22 -0.93 0.07 -0.25 -0.85 0.19
14814 BRD-K37940862 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.24
15049 BRD-K37940862 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15333 BRD-K37940862 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15620 BRD-K37940862 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
16050 BRD-K37940862 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
115086 BRD-K37940862 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).