CMap Candidate Details

Structure:
CMap ID: C01451
Pert ID: BRD-A61154809
Compound Name: gliclazide
Targets: ABCC8
MoA: ATP channel blocker; Insulin secretagogue
SMILES: Cc1ccc(cc1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1
InchiKey: BOVGTQGAOIONJV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91399 BRD-A61154809 HUH7 10 uM 72 h -0.21 -0.86 0.02 0.0 0.0 0.0
100247 BRD-A61154809 U2OS 10 uM 6 h -0.23 -0.94 0.08 0.28 0.98 0.36
123819 BRD-A61154809 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123860 BRD-A61154809 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123929 BRD-A61154809 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124031 BRD-A61154809 JURKAT 1.11 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
124082 BRD-A61154809 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124109 BRD-A61154809 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124146 BRD-A61154809 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
124159 BRD-A61154809 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124212 BRD-A61154809 THP1 1.11 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
124265 BRD-A61154809 YAPC 3.33 uM 24 h -0.17 -0.7 0.0 0.0 0.0 0.0
132182 BRD-A61154809 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132214 BRD-A61154809 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
132245 BRD-A61154809 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).