CMap Candidate Details

Structure:
CMap ID: C14515
Pert ID: BRD-K38003476
Compound Name: clocortolone-pivalate
Targets: NR3C1
MoA: Steroid
SMILES: C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@H]1C(=O)COC(=O)C(C)(C)C
InchiKey: SXYZQZLHAIHKKY-GSTUPEFVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4109 BRD-K38003476 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
4428 BRD-K38003476 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4930 BRD-K38003476 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39693 BRD-K38003476 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40003 BRD-K38003476 HEPG2 10 uM 6 h 0.22 0.93 0.05 -0.33 -1.12 0.93
40274 BRD-K38003476 HT29 10 uM 6 h 0.25 1.03 0.14 -0.35 -1.16 1.11
40811 BRD-K38003476 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41114 BRD-K38003476 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
41449 BRD-K38003476 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95493 BRD-K38003476 A549 4 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
95587 BRD-K38003476 MCF??7.00 4 uM 48 h 0.0 0.0 0.0 -0.25 -0.85 0.19
95713 BRD-K38003476 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96619 BRD-K38003476 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96688 BRD-K38003476 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).