CMap Candidate Details

Structure:
CMap ID: C01452
Pert ID: BRD-A61189834
Compound Name: BRD-A61189834
Targets: XIAP
MoA: XIAP inhibitor
SMILES: CNC(C)C(=O)NC(C(C)C)C(=O)N1CCCC1C(=O)Nc1ccc2[nH]ccc2c1
InchiKey: CPJCDIAPGXTNBU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21955 BRD-A61189834 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22101 BRD-A61189834 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
22389 BRD-A61189834 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22650 BRD-A61189834 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22931 BRD-A61189834 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.18 0.65 0.01
23237 BRD-A61189834 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.34
23677 BRD-A61189834 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23943 BRD-A61189834 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24265 BRD-A61189834 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).