CMap Candidate Details

Structure:
CMap ID: C01457
Pert ID: BRD-A61392169
Compound Name: eliprodil
Targets: GRIN1; GRIN2B
MoA: Glutamate receptor antagonist
SMILES: OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1
InchiKey: GGUSQTSTQSHJAH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6666 BRD-A61392169 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7097 BRD-A61392169 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7247 BRD-A61392169 HA1E 10 uM 24 h 0.2 0.82 0.0 0.24 0.84 0.12
7568 BRD-A61392169 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7788 BRD-A61392169 HT29 10 uM 24 h -0.17 -0.72 0.0 -0.25 -0.84 0.18
8054 BRD-A61392169 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8318 BRD-A61392169 PC3 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
90284 BRD-A61392169 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100248 BRD-A61392169 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).