CMap Candidate Details

Structure:
CMap ID: C14635
Pert ID: BRD-K38449220
Compound Name: seneciphylline
Targets: --
MoA: --
SMILES: C/C=C1/CC(=C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@H](OC1=O)[C@H]32
InchiKey: FCEVNJIUIMLVML-QPSVUOIXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4110 BRD-K38449220 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
4430 BRD-K38449220 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4686 BRD-K38449220 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5081 BRD-K38449220 VCAP 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.6
39133 BRD-K38449220 A375 10 uM 6 h -0.29 -1.21 0.59 0.0 0.0 0.0
39449 BRD-K38449220 A549 10 uM 6 h 0.23 0.95 0.06 -0.32 -1.09 0.83
39694 BRD-K38449220 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40004 BRD-K38449220 HEPG2 10 uM 6 h -0.21 -0.86 0.02 -0.34 -1.14 1.03
40275 BRD-K38449220 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40471 BRD-K38449220 MCF??7.00 10 uM 24 h -0.24 -0.99 0.13 -0.28 -0.95 0.4
41115 BRD-K38449220 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41450 BRD-K38449220 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99914 BRD-K38449220 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).