CMap Candidate Details

Structure:
CMap ID: C14645
Pert ID: BRD-K38477985
Compound Name: malonoben
Targets: EGFR
MoA: Protein tyrosine kinase inhibitor
SMILES: CC(C)(C)c1cc(C=C(C#N)[N+]#[C-])cc(c1O)C(C)(C)C
InchiKey: MKUVGSJPVXTADZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4220 BRD-K38477985 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4431 BRD-K38477985 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4687 BRD-K38477985 PC3 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
4931 BRD-K38477985 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.41 2.02
39134 BRD-K38477985 A375 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.44
39450 BRD-K38477985 A549 10 uM 6 h 0.0 0.0 0.0 -0.52 -1.76 15.65
39695 BRD-K38477985 ASC 10 uM 24 h 0.3 1.26 0.56 0.0 0.0 0.0
40005 BRD-K38477985 HEPG2 10 uM 6 h -0.19 -0.79 0.0 0.0 0.0 0.0
40276 BRD-K38477985 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40620 BRD-K38477985 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40812 BRD-K38477985 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41116 BRD-K38477985 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41451 BRD-K38477985 SKB 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
53583 BRD-K38477985 HUH7 2.5 uM 6 h 0.0 0.0 0.0 -0.45 -1.51 15.35
53659 BRD-K38477985 PHH 10 uM 24 h 0.28 1.16 0.36 -0.29 -0.97 0.45
99915 BRD-K38477985 U2OS 10 uM 6 h 0.22 0.93 0.05 -0.2 -0.67 0.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).