CMap Candidate Details

Structure:
CMap ID: C14767
Pert ID: BRD-K38852836
Compound Name: ganetespib
Targets: HSP90AA1
MoA: HSP inhibitor
SMILES: CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3n(C)ccc3c2)c(O)cc1O
InchiKey: RVAQIUULWULRNW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95546 BRD-K38852836 A549 10 uM 6 h -0.25 -1.06 0.26 0.0 0.0 0.0
95681 BRD-K38852836 U2OS 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
121591 BRD-K38852836 HA1E 0.04 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
129580 BRD-K38852836 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129598 BRD-K38852836 HELA 0.01 uM 24 h -0.33 -1.36 1.06 -0.35 -1.17 1.11
129628 BRD-K38852836 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
129658 BRD-K38852836 MCF??7.00 0.01 uM 24 h 0.25 1.02 0.13 -0.37 -1.24 1.31
129682 BRD-K38852836 PC3 0.01 uM 24 h -0.22 -0.93 0.07 -0.37 -1.25 1.35
129721 BRD-K38852836 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).