CMap Candidate Details

Structure:
CMap ID: C01477
Pert ID: BRD-A62057054
Compound Name: MDL-11939
Targets: HTR2A
MoA: Serotonin receptor antagonist
SMILES: OC(C1CCN(CCc2ccccc2)CC1)c1ccccc1
InchiKey: AXNGJCOYCMDPQG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6669 BRD-A62057054 A375 10 uM 24 h -0.3 -1.26 0.72 0.0 0.0 0.0
7099 BRD-A62057054 A549 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
7249 BRD-A62057054 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7569 BRD-A62057054 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7789 BRD-A62057054 HT29 10 uM 24 h 0.23 0.96 0.07 0.35 1.24 1.24
8270 BRD-A62057054 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8461 BRD-A62057054 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8603 BRD-A62057054 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100253 BRD-A62057054 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).