CMap Candidate Details

Structure:
CMap ID: C14774
Pert ID: BRD-K38868394
Compound Name: MK-0773
Targets: AR
MoA: Androgen receptor modulator
SMILES: CN1[C@@H]2CC[C@H]3[C@@H]4CC[C@H](C(=O)NCc5nc6cccnc6[nH]5)[C@@]4(C)CC[C@@H]3[C@@]2(C)C=C(F)C1=O
InchiKey: GBEUKTWTUSPHEE-JWJWXJQQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123228 BRD-K38868394 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123417 BRD-K38868394 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123453 BRD-K38868394 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
131543 BRD-K38868394 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131578 BRD-K38868394 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131620 BRD-K38868394 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131654 BRD-K38868394 HELA 0.25 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.88
131682 BRD-K38868394 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131714 BRD-K38868394 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
131767 BRD-K38868394 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
131817 BRD-K38868394 MCF10A 0.25 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
131847 BRD-K38868394 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131884 BRD-K38868394 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131949 BRD-K38868394 YAPC 0.03 uM 24 h -0.23 -0.94 0.08 -0.2 -0.68 0.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).