CMap Candidate Details

Structure:
CMap ID: C01480
Pert ID: BRD-A62184259
Compound Name: cycloheximide
Targets: RPL3
MoA: Protein synthesis inhibitor
SMILES: CC1CC(C)C(=O)C(C1)C(O)CC2CC(=O)NC(=O)C2
InchiKey: YPHMISFOHDHNIV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5160 BRD-A62184259 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5271 BRD-A62184259 HA1E 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
5731 BRD-A62184259 HCC515 10 uM 6 h 0.26 1.07 0.19 -0.46 -1.56 15.65
5987 BRD-A62184259 HT29 10 uM 6 h 0.26 1.1 0.24 -0.55 -1.86 15.65
6141 BRD-A62184259 PC3 10 uM 24 h 0.33 1.36 0.97 -0.34 -1.14 1.03
6477 BRD-A62184259 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.6
42024 BRD-A62184259 A549 10 uM 6 h 0.24 1.02 0.13 -0.55 -1.85 15.65
42224 BRD-A62184259 ASC 10 uM 24 h 0.34 1.42 1.09 -0.28 -0.95 0.41
42566 BRD-A62184259 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43267 BRD-A62184259 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43425 BRD-A62184259 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
43733 BRD-A62184259 PHH 10 uM 24 h 0.25 1.05 0.17 -0.37 -1.25 1.35
44020 BRD-A62184259 SKB 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).