CMap Candidate Details

Structure:
CMap ID: C01483
Pert ID: BRD-A62326914
Compound Name: paroxetine
Targets: SLC6A4
MoA: Selective serotonin reuptake inhibitor
SMILES: Fc1ccc(cc1)C2CCNCC2COc3ccc4OCOc4c3
InchiKey: AHOUBRCZNHFOSL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49772 BRD-A62326914 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49952 BRD-A62326914 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50114 BRD-A62326914 HA1E 10 uM 6 h -0.21 -0.86 0.01 0.29 1.01 0.46
50302 BRD-A62326914 HCC515 10 uM 6 h -0.25 -1.02 0.19 -0.25 -0.84 0.17
50466 BRD-A62326914 HT29 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.28
50718 BRD-A62326914 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50890 BRD-A62326914 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50985 BRD-A62326914 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).