CMap Candidate Details

Structure:
CMap ID: C14857
Pert ID: BRD-K39111395
Compound Name: BCL2-inhibitor
Targets: BCL2
MoA: BCL inhibitor
SMILES: COc1ccc([N+][O-])c(CCc2cc(OC)ccc2[N+][O-])c1
InchiKey: YPSXFMHXRZAGTG-UHFFFAOYSA-N
Compound Aliases: BCL-2-INHIBITOR

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3016 BRD-K39111395 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3364 BRD-K39111395 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3496 BRD-K39111395 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3786 BRD-K39111395 VCAP 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
41767 BRD-K39111395 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41932 BRD-K39111395 A549 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
42359 BRD-K39111395 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42685 BRD-K39111395 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42987 BRD-K39111395 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43318 BRD-K39111395 MCF??7.00 10 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
43549 BRD-K39111395 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43847 BRD-K39111395 PHH 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).