CMap Candidate Details

Structure:
CMap ID: C01487
Pert ID: BRD-A62434282
Compound Name: goserelin
Targets: GNRHR
MoA: Luteinizing hormone releasing hormone agonist
SMILES: CC(C)CC(NC(=O)C(COC(C)(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1c[nH]cn1)NC(=O)C1CCC(=O)N1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCCC1C(=O)NNC(N)=O
InchiKey: BLCLNMBMMGCOAS-KJLMDEBVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21903 BRD-A62434282 A375 10 uM 6 h 0.0 0.0 0.0 0.37 1.33 1.72
22392 BRD-A62434282 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22653 BRD-A62434282 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22934 BRD-A62434282 HEPG2 10 uM 6 h 0.25 1.04 0.14 -0.22 -0.74 0.05
23240 BRD-A62434282 HT29 10 uM 6 h 0.22 0.91 0.04 0.25 0.87 0.18
23518 BRD-A62434282 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23793 BRD-A62434282 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24086 BRD-A62434282 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).