CMap Candidate Details

Structure:
CMap ID: C14887
Pert ID: BRD-K39188321
Compound Name: betamethasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InchiKey: UREBDLICKHMUKA-DVTGEIKXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2879 BRD-K39188321 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3193 BRD-K39188321 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3497 BRD-K39188321 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3788 BRD-K39188321 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44386 BRD-K39188321 A375 10 uM 6 h 0.0 0.0 0.0 0.34 1.22 1.15
44701 BRD-K39188321 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44950 BRD-K39188321 ASC 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
45246 BRD-K39188321 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45516 BRD-K39188321 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45817 BRD-K39188321 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.7
46067 BRD-K39188321 NPC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
46382 BRD-K39188321 PHH 10 uM 24 h 0.25 1.03 0.14 0.0 0.0 0.0
46702 BRD-K39188321 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99922 BRD-K39188321 U2OS 4 uM 6 h -0.22 -0.9 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).