CMap Candidate Details

Structure:
CMap ID: C01491
Pert ID: BRD-A62525898
Compound Name: prednisone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@]12CC(=O)C3C(CCC4=CC(=O)C=C[C@]34C)C1CC[C@]2(O)C(=O)CO
InchiKey: XOFYZVNMUHMLCC-BDQMTFAOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5536 BRD-A62525898 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6440 BRD-A62525898 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
37529 BRD-A62525898 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37838 BRD-A62525898 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38376 BRD-A62525898 NPC 10 uM 24 h 0.24 1.0 0.1 0.0 0.0 0.0
38652 BRD-A62525898 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100257 BRD-A62525898 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124929 BRD-A62525898 A375 0.125 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
124957 BRD-A62525898 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124991 BRD-A62525898 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125018 BRD-A62525898 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125049 BRD-A62525898 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125101 BRD-A62525898 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125148 BRD-A62525898 THP1 0.37 uM 24 h 0.21 0.88 0.01 0.21 0.74 0.04
125197 BRD-A62525898 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133034 BRD-A62525898 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133141 BRD-A62525898 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133189 BRD-A62525898 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
133216 BRD-A62525898 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
133283 BRD-A62525898 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).