CMap Candidate Details

Structure:
CMap ID: C14912
Pert ID: BRD-K39256324
Compound Name: rottlerin
Targets: --
MoA: --
SMILES: CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c(C(=O)C=Cc3ccccc3)c4OC(C)(C)C=Cc4c2O)c1O
InchiKey: DEZFNHCVIZBHBI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5324 BRD-K39256324 HA1E 10 uM 24 h 0.0 0.0 0.0 0.17 0.6 0.0
5622 BRD-K39256324 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
5909 BRD-K39256324 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.48 -1.6 15.65
6093 BRD-K39256324 MCF??7.00 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
6543 BRD-K39256324 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44387 BRD-K39256324 A375 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
44581 BRD-K39256324 A549 10 uM 24 h -0.16 -0.68 0.0 -0.24 -0.82 0.14
44951 BRD-K39256324 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46068 BRD-K39256324 NPC 10 uM 24 h 0.25 1.06 0.18 -0.35 -1.18 1.15
46383 BRD-K39256324 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46703 BRD-K39256324 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119683 BRD-K39256324 HT29 10 uM 24 h 0.0 0.0 0.0 0.39 1.37 2.01
119720 BRD-K39256324 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119806 BRD-K39256324 PC3 10 uM 24 h 0.19 0.81 0.0 -0.31 -1.06 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).