CMap Candidate Details

Structure:
CMap ID: C01497
Pert ID: BRD-A62809825
Compound Name: thapsigargin
Targets: ATP2A1
MoA: ATPase inhibitor
SMILES: CCCCCCCC(=O)OC1C(OC(=O)/C(=C/C)/C)C(=C2C3OC(=O)C(C)(O)C3(O)C(CC(C)(OC(=O)C)C12)OC(=O)CCC)C
InchiKey: IXFPJGBNCFXKPI-YBFXNURJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8880 BRD-A62809825 A375 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
9074 BRD-A62809825 A549 10 uM 24 h -0.21 -0.89 0.04 -0.4 -1.33 1.75
9604 BRD-A62809825 H1299 10 uM 6 h 0.23 0.96 0.07 0.0 0.0 0.0
9871 BRD-A62809825 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10247 BRD-A62809825 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10679 BRD-A62809825 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10911 BRD-A62809825 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11251 BRD-A62809825 MCF??7.00 10 uM 6 h -0.31 -1.28 0.74 0.0 0.0 0.0
11352 BRD-A62809825 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
11924 BRD-A62809825 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.54
12215 BRD-A62809825 NOMO1 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.5
12427 BRD-A62809825 PC3 10 uM 24 h -0.23 -0.98 0.12 0.21 0.74 0.04
12676 BRD-A62809825 SW480 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
12927 BRD-A62809825 THP1 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.33
13542 BRD-A62809825 VCAP 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
90439 BRD-A62809825 HL60 4 uM 2 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).